This is the introductory course in the nanosystems area. It introduces students to the principles and applications of nanosystems. The course begins with an introduction to the nanometer scale phenomena. It then introduces students to the basic elements resulting in nanosystems: nanoscale materials, processes, and devices. It also provides students with a basic understanding of the tools and approaches that are used for the measurement and characterization of nanosystems, and their modeling and simulation. Moreover, the course covers the applications of nanosystems in a wide range of industries, including information technology, energy, medicine, and consumer goods. The course concludes with a discussion of the societal and economical significance of these applications, including benefits and potential risks. Class Notes: If you are an undergraduate student, please see your advisor for permission to register.