This is a new course focusing on therapeutic approaches that target various features of the immune system to infections, cancer or immune based diseases such as autoimmunity. Topics will include fundamental concepts of immunology as these apply to therapies, and types of immunotherapy such as biologics, cell-based therapies, and therapeutic vaccines. The course will also provide overviews of different immunotherapeutic approaches, specific examples of therapeutic targets featuring both licensed and experimental small molecules, the challenges of immune-based therapies, and overviews of the development, features, and challenges of therapeutic vaccines. The course will also feature lectures by invited experts in various fields related to immune therapy and vaccine development. Students are encouraged, but not required, to take MICB-612 (Immunology) or an equivalent, prior to this course.