The primary objective of this course is to learn the principles of diverse modern analytical instruments in the qualitative and quantitative characterizations of chemical systems in a research-oriented environment. This course is designed to give you practical experience in using modern analytical instrumentation and to provide you with the background theory and principles of operation. As such, it has both a laboratory and lecture component. In the lectures you will learn about the chemical or physical principles used during the measurement, how the instrument actually takes the measurement and some of the techniques used to increase accuracy, precision and sensitivity. Topics to be covered in lecture include: spectroscopy, electrochemistry, NMR spectroscopy, mass spectrometry, chromatography, and electro-separations. In the laboratory, you will put this knowledge into practice by performing various experiments designed to provide examples of the usefulness of the particular instrument or technique. As in many chemistry classes, you must develop good physical manipulation skills. However, it is important to remember that many different types of a particular instrument exist. We don't want you to be an "expert" on one instrument but learn the operating principles of the technique so that you will be able to understand and operate a wide range of instruments based on this knowledge. Most people who follow a scientific career will use instruments at some time to take measurements of various chemical or physical properties. Even people who follow a non-scientific career will often need to interpret data and assess its quality (accuracy and reliability) and determine if the data was recorded in a sensible way using an appropriate instrument. .